What are whole exome sequencing and whole genome sequencing?

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Whole exome sequencing and whole genome sequencing are two methods of DNA sequencing. Both these are modern, based on the latest technology and allows large amounts of DNA to be quickly sequenced. These techniques are often called next-generation sequencing (or next-gen sequencing).

Exons are DNA fragments that provide instructions for protein formation in the body. They are said to comprise 1% of a person’s genome. All the exons in a genome are collectively known as exome and their sequencing is called whole exome sequencing.

Whole genome sequencing (WGS) is a test which is used to determine nearly all of the 3 billion nucleotides present in a person’s complete DNA sequence.

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